Duox1 - dual oxidase 1 Gene

Also Known as Duox2; LNOX1; LNOX2; THOX1; THOX2; NOXEF1; NOXEF2; P138-TOX; 9930101G15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 99439

Summary

Predicted to enable superoxide-generating NAD(P)H oxidase activity. Acts upstream of or within Reactive Oxygen Species metabolic process. Located in plasma membrane. Is expressed in brain; placenta; and thyroid gland. Orthologous to human DUOX1 (dual oxidase 1). [provided by Alliance of Genome Resources, Apr 2022]

Duox1 Products (1)

mRNA Protein Name
NM_001099297.1 NP_001092767.1 dual oxidase 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20233719 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within reactive oxygen species metabolic process IGI
IGI: Inferred from genetic interaction
20233719 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
20233719 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dual oxidase 1

  • dual oxidase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-174817 NOX5-IN-1 Inhibitor / Unkown
HY-174818 NOX5-IN-2 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Duox1 NCBI NCBI:53905