Usp53 - ubiquitin specific peptidase 53 Gene

Also Known as Sp6; mbo; Phxr3; mKIAA1350

Species: Mus musculus

Gene Type: protein coding
Gene ID: 99526

Summary

Predicted to enable thiol-dependent Deubiquitinase. Acts upstream of or within several processes, including neuron apoptotic process; response to auditory stimulus; and sensory perception of sound. Located in cell-cell junction. Is expressed in olfactory epithelium; submandibular gland primordium; and tooth. Orthologous to human USP53 (ubiquitin specific peptidase 53). [provided by Alliance of Genome Resources, Apr 2022]

Usp53 Products (8)

mRNA Protein Name
NM_001411523.1 NP_001398452.1 inactive ubiquitin carboxyl-terminal hydrolase 53 isoform 1
NM_001411527.1 NP_001398456.1 inactive ubiquitin carboxyl-terminal hydrolase 53 isoform 2
NM_001411528.1 NP_001398457.1 inactive ubiquitin carboxyl-terminal hydrolase 53 isoform 2
NM_001411529.1 NP_001398458.1 inactive ubiquitin carboxyl-terminal hydrolase 53 isoform 2
NM_001411530.1 NP_001398459.1 inactive ubiquitin carboxyl-terminal hydrolase 53 isoform 3
NM_001411531.1 NP_001398460.1 inactive ubiquitin carboxyl-terminal hydrolase 53 isoform 4
NM_001411532.1 NP_001398461.1 inactive ubiquitin carboxyl-terminal hydrolase 53 isoform 5
NM_133857.4 NP_598618.1 inactive ubiquitin carboxyl-terminal hydrolase 53 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
NOT enables deubiquitinase activity IDA
IDA: Inferred from direct assay
26609154 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
26609154 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within action potential IMP
IMP: Inferred from mutant phenotype
26609154 MGI
acts upstream of or within epithelial cell apoptotic process IMP
IMP: Inferred from mutant phenotype
26609154 MGI
acts upstream of or within neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
26609154 MGI
acts upstream of or within outer hair cell apoptotic process IMP
IMP: Inferred from mutant phenotype
26609154 MGI
NOT acts upstream of or within protein deubiquitination IDA
IDA: Inferred from direct assay
26609154 MGI
acts upstream of or within response to auditory stimulus IMP
IMP: Inferred from mutant phenotype
26609154 MGI
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
17329413 MGI
Cellular Component GO Annotation Evidence References Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
26609154 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inactive ubiquitin carboxyl-terminal hydrolase 53

  • inactive ubiquitin-specific peptidase 53

  • per-hexamer repeat gene 3

  • per-hexamer repeat protein 3

  • protein mambo

  • ubiquitin specific protease 53

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15564 USP53 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-184244 CAS-010 Inhibitor / Unkown
HY-RS20514 Usp53 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27023 Usp53 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp53 NCBI NCBI:54532