1. GPCR/G Protein Neuronal Signaling
  2. Neurokinin Receptor
  3. [Glp5] Substance P (5-11)

[Glp5] Substance P (5-11) is an octapeptide. [Glp5] Substance P (5-11) is one of the main substance P fragments in rat central nervous system (CNS). [Glp5] Substance P (5-11) locally modulates dopamine release in rat striatum.

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[Glp5] Substance P (5-11) Chemical Structure

[Glp5] Substance P (5-11) Chemical Structure

CAS No. : 56104-22-4

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Description

[Glp5] Substance P (5-11) is an octapeptide. [Glp5] Substance P (5-11) is one of the main substance P fragments in rat central nervous system (CNS). [Glp5] Substance P (5-11) locally modulates dopamine release in rat striatum[1].

In Vitro

[Glp5] Substance P (5-11) (0.12 nM-10 μM; rat striatum) modifies spontaneous dopamine outflow with a significant increase in dopamine outflow at 0.1 nM and a smaller effect at 1 nM, whereas concentrations lower than 0.1 nM or higher than 1 nM failed to modify dopamine release. [Glp5] Substance P (5-11) and K+ has additive effect, promoting the release of dopamine[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

852.01

Formula

C41H57N9O9S

CAS No.
Sequence Shortening

Glp-QFFGLM-NH2

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References
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[Glp5] Substance P (5-11) Related Classifications

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[Glp5] Substance P (5-11)
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