Glutaminyl cyclase/CB2R modulator-1
Glutaminyl cyclase/CB2R modulator-1 (Compound 18) acts as an inhibitor of glutaminyl cyclase (QC) (IC50 = 0.65 μM) and an agonist of cannabinoid receptor type 2 (CB2R) (EC50 = 0.32 μM). Glutaminyl cyclase/CB2R modulator-1 can be used for the research of Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 3105939-80-5
- Formula: C28H30N4O3
- Molecular Weight:470.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 3105939-80-5
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Molecular Weight 470.56
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Formula C28H30N4O3
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SMILES
O=C(NC1=CC=CC=C1)C2=CC(C3=CC=CC=C3NCCCN4C=NC=C4C)=CC(OC)=C2OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glutaminyl cyclase/CB2R modulator-1 Related Classifications
HY-187205 Related Classifications
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