GSK2236805
GSK2236805 is a potent hepatitis C virus inhibitor with pEC50 values of 10.4, 11.1 for HCV genotype 1a (gt1a) and gt1b, respectively.
For research use only. We do not sell to patients.
- CAS No.: 1256390-53-0
- Formula: C42H52N8O8
- Molecular Weight:796.91
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
pEC50: 10.4 (gt1a); 11.1 µM (gt1b)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | EC50 |
0.0074 nM
Compound: 2, GSK2336805
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Antiviral activity against HCV genotype 1b infected in human Huh7 cells after 3 days by cell-based replicon assay
Antiviral activity against HCV genotype 1b infected in human Huh7 cells after 3 days by cell-based replicon assay
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[PMID: 25148100] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1256390-53-0
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Molecular Weight 796.91
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Formula C42H52N8O8
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SMILES
O=C(OC)N[C@H](C(N1[C@H](C2=NC(C3=CC=C(C4=CC=C(C5=CNC([C@H](C6)N(C([C@@H](NC(OC)=O)C(C)C)=O)CC76OCCO7)=N5)C=C4)C=C3)=CN2)CCC1)=O)C(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GSK2236805 Related Classifications
HY-12731 Related Classifications
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