Heme Oxygenase-1-IN-1 hydrochloride (Standard)
Heme Oxygenase-1-IN-1 hydrochloride (Standard) is the analytical standard of Heme Oxygenase-1-IN-1 (hydrochloride) (HY-111798A). This product is intended for research and analytical applications. Heme Oxygenase-1-IN-1 (Compound 2) hydrochloride is a heme oxygenase 1 (HO-1) inhibitor with an IC50 of 0.25 μM.
For research use only. We do not sell to patients.
- CAS No.: 1092851-70-1
- Formula: C13H16BrClN2
- Molecular Weight:315.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1092851-70-1
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Molecular Weight 315.64
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Formula C13H16BrClN2
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SMILES
BrC1=CC=C(CCCCN2C=CN=C2)C=C1.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Floresta G, et al. Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis. Bioorg Chem. 2018 Dec;81:334-339. [Content Brief]
[2]. Zeng X, et al. Mitochondrial GRIM-19 loss in parietal cells promotes spasmolytic polypeptide-expressing metaplasia through NLR family pyrin domain-containing 3 (NLRP3)-mediated IL-33 activation via a reactive oxygen species (ROS) -NRF2- Heme oxygenase-1(HO-1)-NF-кB axis. Free Radic Biol Med. 2023 Jun;202:46-61. [Content Brief]
[3]. Wang X, et al. Mitochondrial GRIM-19 deficiency facilitates gastric cancer metastasis through oncogenic ROS-NRF2-HO-1 axis via a NRF2-HO-1 loop. Gastric Cancer. 2021 Jan;24(1):117-132. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)