HIV-1 inhibitor-55
HIV-1 inhibitor-55 (compound 4d) inhibits WT HIV-1 with an EC50 value of 8.6 nM. HIV-1 inhibitor-55 also shows inhibitory potency against single and double HIV-1 mutants. HIV-1 inhibitor-55 can be used for the research of virus infection.
For research use only. We do not sell to patients.
- CAS No.: 2771211-73-3
- Formula: C28H32N6O4S
- Molecular Weight:548.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | CC50 |
19 μM
Compound: 4d
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Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 5 days by MTT spectrophotometric assay
Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 5 days by MTT spectrophotometric assay
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[PMID: 36640458] |
HIV-1 inhibitor-55 shows inhibitory potency against WT HIV-1 with an EC50 value of 8.6 nM[1]. HIV-1 inhibitor-55 shows potent activities against reverse transcriptase (RT) HIV-1 mutants L100I, K103N, Y181C, Y188L, E138K and F227L + V106A with EC50 values of 1.1, 0.12, 0.36, 0.75, 0.033 and 3.06 μM, respectively[1]. HIV-1 inhibitor-55 inhibits WT HIV-1 RT activity with an IC50 value of 0.11 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2771211-73-3
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Molecular Weight 548.66
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Formula C28H32N6O4S
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SMILES
CC1=CC(C)=C(C(C)=C1)OC2=CC=NC(NC3CCN(CC3)C(C4=CC5=C(N4)C=CC(NS(C)(=O)=O)=C5)=O)=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HIV-1 inhibitor-55 Related Classifications
HY-152560 Related Classifications
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