hMAO-B-IN-7
hMAO-B-IN-7 (compound 11n) is a potent and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B), with the IC50 value of 0.79±0.05 μM. hMAO-B-IN-7 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research.
For research use only. We do not sell to patients.
- CAS No.: 2955577-14-5
- Formula: C23H19FN2O5
- Molecular Weight:422.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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hMAO-B 0.79 μM (IC50) |
Chemical Information
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CAS No. 2955577-14-5
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Molecular Weight 422.41
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Formula C23H19FN2O5
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SMILES
CC1=C(C(C=CN1CCN2C(C3=CC=C(C=C3C2=O)OCC4=CC=C(C=C4)F)=O)=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)