Anticancer agent 143
Anticancer agent 143 (compound 369) is a dual PTPN2/PTP1B inhibitor with IC50 values <2.5 nM. Anticancer agent 143 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2948339-38-4
- Formula: C19H15BrF2N3O6PS2
- Molecular Weight:594.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
IC50: ＜2.5 nM (PTPN2/PTP1B)[1].
Chemical Information
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CAS No. 2948339-38-4
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Molecular Weight 594.34
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Formula C19H15BrF2N3O6PS2
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SMILES
O=P(O)(C(F)(C1=C(Br)C2=C(C(OCC3=CC=C(S(=O)(C)=O)C=C3)=CC(C4=CN=NN4)=C2)S1)F)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 143 Related Classifications
HY-156607 Related Classifications
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