2. Metabolic Enzyme/Protease
  3. Indoleamine 2,3-Dioxygenase (IDO)
  4. IDO1/TDO-IN-17

IDO1/TDO-IN-17 is an IDO1/TDO inhibitor with human IDO1 IC50 ~280 μmol/L and human TDO IC50 204 μmol/L. IDO1/TDO-IN-17 binds to the heme-iron of IDO1. IDO1/TDO-IN-17 can be used for the research of cancer.

For research use only. We do not sell to patients.

IDO1/TDO-IN-17

IDO1/TDO-IN-17 Chemical Structure

CAS No. : 537010-02-9

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IDO1/TDO-IN-17 Related Antibodies

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Description

IDO1/TDO-IN-17 is an IDO1/TDO inhibitor with human IDO1 IC50 ~280 μmol/L and human TDO IC50 204 μmol/L. IDO1/TDO-IN-17 binds to the heme-iron of IDO1. IDO1/TDO-IN-17 can be used for the research of cancer[1].

IC50 & Target[1]

IDO1

~280 μM (IC50)

In Vitro

IDO1/TDO-IN-17 (Compound 19) inhibits recombinant human IDO1 with an IC50 of ~280 μmol/L and recombinant human TDO with an IC50 of 204 μmol/L, binding to the heme-iron of hIDO1 but not hTDO[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

IDO1/TDO-IN-17 Related Antibodies
Molecular Weight

302.35

Formula

C15H14N2O3S
CAS No.
SMILES

O=S(O)(C1=NC2=C(N1C(C)C3=CC=CC=C3)C=CC=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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IDO1/TDO-IN-17 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IDO1/TDO-IN-17537010-02-9Indoleamine 2,3-Dioxygenase (IDO)cancerheme-containing proteinSoret bandrecombinant human TDOIDO1recombinant human IDO1heme-ironTDOInhibitorinhibitorinhibit

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