IDO1/TDO-IN-17
IDO1/TDO-IN-17 is an IDO1/TDO inhibitor with human IDO1 IC50 ~280 μmol/L and human TDO IC50 204 μmol/L. IDO1/TDO-IN-17 binds to the heme-iron of IDO1. IDO1/TDO-IN-17 can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 537010-02-9
- Formula: C15H14N2O3S
- Molecular Weight:302.35
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
IDO1 ~280 μM (IC50) |
In Vitro
IDO1/TDO-IN-17 (Compound 19) inhibits recombinant human IDO1 with an IC50 of ~280 μmol/L and recombinant human TDO with an IC50 of 204 μmol/L, binding to the heme-iron of hIDO1 but not hTDO[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
-
CAS No. 537010-02-9
-
Molecular Weight 302.35
-
Formula C15H14N2O3S
-
SMILES
O=S(O)(C1=NC2=C(N1C(C)C3=CC=CC=C3)C=CC=C2)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IDO1/TDO-IN-17 Related Classifications
HY-184104 Related Classifications
Powered by Bioz