2. Immunology/Inflammation
  3. IFNAR
  4. IFN-γ Antagonist 1

IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) is an antagonist of interferon γ (IFN γ). IFN-γ Antagonist 1 inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells with an IC50 value of approximately 35 μM. IFN-γ Antagonist 1 has potential applications in immune regulation.

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IFN-γ Antagonist 1 Chemical Structure

IFN-γ Antagonist 1 Chemical Structure

CAS No. : 158040-83-6

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Description

IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) is an antagonist of interferon γ (IFN γ). IFN-γ Antagonist 1 inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells with an IC50 value of approximately 35 μM. IFN-γ Antagonist 1 has potential applications in immune regulation[1].

Molecular Weight

2629.04

Formula

C115H194N34O34S
CAS No.
Sequence

Ala-Tyr-{Cys(Acm)}-Arg-Asp-Gly-Lys-Ile-Gly-Pro-Pro-Lys-Leu-{α-Asp}-Ile-Arg-Lys-{α-Glu}-{α-Glu}-Lys-Gln-Ile
Sequence Shortening

AY-{C<Acm>}-RDGKIGPPKL-{α-D}-IRK-{α-E}-{α-E}-KQI
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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IFN-γ Antagonist 1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IFN-γ Antagonist 1158040-83-6IFNARInterferon-α/β receptorInterferon-alpha/beta receptorColon 205 cellsInhibitorinhibitorinhibit

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