1. Apoptosis
  2. Apoptosis
  3. Incensole Acetate

Incensole Acetate 

Cat. No.: HY-N4098 Purity: 99.08%
Handling Instructions

Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25–35-triggered apoptosis in hOBNSCs.

For research use only. We do not sell to patients.

Incensole Acetate Chemical Structure

Incensole Acetate Chemical Structure

CAS No. : 34701-53-6

Size Price Stock Quantity
5 mg USD 134 In-stock
Estimated Time of Arrival: December 31
10 mg USD 229 In-stock
Estimated Time of Arrival: December 31
25 mg USD 457 In-stock
Estimated Time of Arrival: December 31
50 mg USD 686 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25–35-triggered apoptosis in hOBNSCs[1].

In Vitro

Incensole acetate (100 μM; pre-treatment 4 hours) significantly ameliorates Aβ 25–35-induced cell death, a 48–52% decrease in cell viability at Aβ25–35 is restored to 85–89% upon pre-treatment with IA[1].
Incensole acetate (5-100 μM) pretreatment reverses increase in the mRNA and protein level of Bax, caspase 8, cyto c and decrease in the mRNA and protein level of Bcl2 induced by Aβ 25–35 in hOBNSCs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Human olfactory bulb neural stem cells
Concentration: 100 μM
Incubation Time: Pre-treatment 4 hours
Result: Increased hOBNSCs cell viability induced by Aβ 25-35.
Molecular Weight

348.52

Formula

C22H36O3

CAS No.
SMILES

CC([[email protected]@]12C/C=C(C)/CC/C=C(C)/CC[[email protected]](OC(C)=O)[[email protected]@](O2)(C)CC1)C

Structure Classification
Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (286.93 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8693 mL 14.3464 mL 28.6928 mL
5 mM 0.5739 mL 2.8693 mL 5.7386 mL
10 mM 0.2869 mL 1.4346 mL 2.8693 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.17 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (7.17 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.17 mM); Clear solution

*All of the co-solvents are available by MCE.
References
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Product Name:
Incensole Acetate
Cat. No.:
HY-N4098
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