Iso-H7 dihydrochloride
Based on 1 Customer Validation
Iso-H7 dihydrochloride is an inhibitor of protein kinase with IC50 values of 22 and 34 μM to PKC and PKA respectively. Iso-H7 dihydrochloride has negative control of PKA on satellite cell myogenesis.
For research use only. We do not sell to patients.
- Purity: 99.06%
- CAS No.: 140663-38-3
- Formula: C14H19Cl2N3O2S
- Molecular Weight:364.29
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 140663-38-3
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Appearance Solid
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Molecular Weight 364.29
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Formula C14H19Cl2N3O2S
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Color White to off-white
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SMILES
O=S(C1=CC=CC2=C1C=CN=C2)(N3CC(C)NCC3)=O.[H]Cl.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 100 mg/mL (274.51 mM)
DMSO : 50 mg/mL (137.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 2.7451 mL | 13.7253 mL | 27.4507 mL | 68.6266 mL |
| 5 mM | 0.5490 mL | 2.7451 mL | 5.4901 mL | 13.7253 mL | |
| 10 mM | 0.2745 mL | 1.3725 mL | 2.7451 mL | 6.8627 mL | |
| 15 mM | 0.1830 mL | 0.9150 mL | 1.8300 mL | 4.5751 mL | |
| 20 mM | 0.1373 mL | 0.6863 mL | 1.3725 mL | 3.4313 mL | |
| 25 mM | 0.1098 mL | 0.5490 mL | 1.0980 mL | 2.7451 mL | |
| 30 mM | 0.0915 mL | 0.4575 mL | 0.9150 mL | 2.2876 mL | |
| 40 mM | 0.0686 mL | 0.3431 mL | 0.6863 mL | 1.7157 mL | |
| 50 mM | 0.0549 mL | 0.2745 mL | 0.5490 mL | 1.3725 mL | |
| 60 mM | 0.0458 mL | 0.2288 mL | 0.4575 mL | 1.1438 mL | |
| 80 mM | 0.0343 mL | 0.1716 mL | 0.3431 mL | 0.8578 mL | |
| 100 mM | 0.0275 mL | 0.1373 mL | 0.2745 mL | 0.6863 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.