Iso-H7 dihydrochloride

Name: Iso-H7 dihydrochloride
Brand: MedChemExpress
SKU: HY-126376
Rating: 4.5 (0 reviews)

Cat. No.: HY-126376 Pureza: 99.06%: Ficha de datos
COA

SDS
Instrucciones de manejo
FAQs
Technical Support

Iso-H7 dihydrochloride is an inhibitor of protein kinase with IC₅₀ values of 22 and 34 μM to PKC and PKA respectively. Iso-H7 dihydrochloride has negative control of PKA on satellite cell myogenesis.

Para uso exclusivo en investigación. No vendemos a pacientes.

Iso-H7 dihydrochloride Estructura química

No. CAS : 140663-38-3

Tamaño	Stock	Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	En stock	Estimated Time of Arrival: December 31
Solid
1 mg	En stock	Estimated Time of Arrival: December 31
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	Obtener un presupuesto
200 mg	Obtener un presupuesto

or Consulta para venta a granel

* Seleccione Cantidad antes de agregar artículos.

This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 1 Customer Validation

Recomendaciones destacadas

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Ver todos los productos específicos de isoformas PKC:

Ver todas las isoformas

PKC PKCα PKCβ PKCγ PKCδ PKCε PKCη PKCζ PKCθ PKCμ PKC-ι ℩ PKCι

Ver todos los productos específicos de isoformas PKA:

Ver todas las isoformas

PKA PKAR PKACα

Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

Peso molecular

364.29

Fòrmula

C₁₄H₁₉Cl₂N₃O₂S

No. CAS

140663-38-3

Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC=CC2=C1C=CN=C2)(N3CC(C)NCC3)=O.[H]Cl.[H]Cl

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

H₂O : ≥ 100 mg/mL (274.51 mM)

DMSO : 50 mg/mL (137.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7451 mL	13.7253 mL	27.4507 mL
5 mM	0.5490 mL	2.7451 mL	5.4901 mL
10 mM	0.2745 mL	1.3725 mL	2.7451 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Pureza y Documentación

Purity: 99.06%

Select Batch:

Ficha de datos (275 KB) SDS (393 KB)

COA (255 KB) HNMR (277 KB) LCMS (96 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. C Lagord, et al. Satellite cell myogenesis is highly stimulated by the kinase inhibitor iso-H7: comparison with HA1004 and staurosporine effects. Biochem Biophys Res Commun. 1993, 191, 3. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	2.7451 mL	13.7253 mL	27.4507 mL	68.6266 mL
	5 mM	0.5490 mL	2.7451 mL	5.4901 mL	13.7253 mL
	10 mM	0.2745 mL	1.3725 mL	2.7451 mL	6.8627 mL
	15 mM	0.1830 mL	0.9150 mL	1.8300 mL	4.5751 mL
	20 mM	0.1373 mL	0.6863 mL	1.3725 mL	3.4313 mL
	25 mM	0.1098 mL	0.5490 mL	1.0980 mL	2.7451 mL
	30 mM	0.0915 mL	0.4575 mL	0.9150 mL	2.2876 mL
	40 mM	0.0686 mL	0.3431 mL	0.6863 mL	1.7157 mL
	50 mM	0.0549 mL	0.2745 mL	0.5490 mL	1.3725 mL
	60 mM	0.0458 mL	0.2288 mL	0.4575 mL	1.1438 mL
	80 mM	0.0343 mL	0.1716 mL	0.3431 mL	0.8578 mL
	100 mM	0.0275 mL	0.1373 mL	0.2745 mL	0.6863 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.