Faim2 - Fas apoptotic inhibitory molecule 2 Gene

Also Known as Lfg; Lfg2; NMP25; Nmp35; Tmbim2; 2900002L20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72393

Summary

Involved in cerebellar Purkinje cell differentiation; cerebellar granular layer development; and regulation of neuron apoptotic process. Acts upstream of or within negative regulation of apoptotic signaling pathway; negative regulation of neuron apoptotic process; and response to ischemia. Located in Golgi apparatus; endoplasmic reticulum; and membrane raft. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and white fat. Orthologous to human FAIM2 (Fas apoptotic inhibitory molecule 2). [provided by Alliance of Genome Resources, Apr 2022]

Faim2 Products (2)

mRNA Protein Name
NM_001038658.2 NP_001033747.1 protein lifeguard 2 isoform 2
NM_028224.4 NP_082500.2 protein lifeguard 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
26582200 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
21209208 MGI
involved in cerebellar Purkinje cell differentiation IMP
IMP: Inferred from mutant phenotype
21957071 MGI
involved in cerebellar Purkinje cell layer development IMP
IMP: Inferred from mutant phenotype
21957071 MGI
involved in cerebellar granular layer development IMP
IMP: Inferred from mutant phenotype
21957071 MGI
involved in cerebellum development IMP
IMP: Inferred from mutant phenotype
21957071 MGI
acts upstream of or within negative regulation of apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
21209208 MGI
acts upstream of or within negative regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
21209208 MGI
acts upstream of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
21209208 MGI
involved in regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
17635665 MGI
acts upstream of or within response to ischemia IMP
IMP: Inferred from mutant phenotype
21209208 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
26582200 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
26582200 MGI
located in membrane IDA
IDA: Inferred from direct assay
26582200 MGI
located in membrane raft IDA
IDA: Inferred from direct assay
17635665 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein lifeguard 2

  • neural membrane protein 35

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04675 FAIM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20922 Faim2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27439 Faim2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Faim2 NCBI NCBI:23017