Oosponol
Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.Oospongol has strong antifungal activity against many antagonistic fungi.
For research use only. We do not sell to patients.
- CAS No.: 146-04-3
- Formula: C11H8O5
- Molecular Weight:220.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Spontaneously hypertensive rats[1]
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Dosage:6.25 mg/kg, 3.1 mg/kg
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Administration:Intraperitoneal injection, once.
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Result:The intraperitoneal injection of 6.25 mg/kg lowered the pressure from 186 mm to 138~112 mm, the intraperitoneal injection of 3.1 mg/kg lowered the pressure from 185 mm to 164~131 mm[1].
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Animal Model:Spontaneously hypertensive rats[1]
-
Dosage:6.25 mg/kg, 3.1 mg/kg
-
Administration:Intraperitoneal injection, once.
-
Result:The intraperitoneal injection of 6.25 mg/kg lowered the pressure from 186 mm to 138~112 mm, the intraperitoneal injection of 3.1 mg/kg lowered the pressure from 185 mm to 164~131 mm.
Chemical Information
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CAS No. 146-04-3
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Molecular Weight 220.18
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Formula C11H8O5
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SMILES
O=C1OC=C(C2=C1C(O)=CC=C2)C(CO)=O
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Structure Classification
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Initial Source
Gloeophyllum abietinum
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Umezawa H, et al.. Dopamine -hydroxylase inhibitor produced by Gloeophyllum striatum and its identity with oosponol. J Antibiot (Tokyo). 1972 Apr;25(4):239-42. [Content Brief]
[2]. Sonnenbichler J,et al. Influence of the Gloeophyllum metabolite oosponol and some synthetic analogues on protein and RNA synthesis in target cells. Eur J Biochem. 1997 May 15;246(1):45-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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