146-04-3
146-04-3
Chemical Structure
Oosponol
- CAS No.: 146-04-3
- Formula:C11H8O5
- Molecular Weight:220.18
IUPAC Name: 8-hydroxy-4-(2-hydroxyacetyl)-1H-isochromen-1-one
InChIKey: WRIZJEREXIDJCC-UHFFFAOYSA-N
SMILES: O=C1OC=C(C2=C1C(O)=CC=C2)C(CO)=O
Biological Activity: Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.Oospongol has strong antifungal activity against many antagonistic fungi[1][2].
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Oosponol | Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.Oospongol has strong antifungal activity against many antagonistic fungi. | |||||||||||||||||||||
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References
- [1]. Umezawa H, et al.. Dopamine -hydroxylase inhibitor produced by Gloeophyllum striatum and its identity with oosponol. J Antibiot (Tokyo). 1972 Apr;25(4):239-42. [Content Brief]
- [2]. Sonnenbichler J,et al. Influence of the Gloeophyllum metabolite oosponol and some synthetic analogues on protein and RNA synthesis in target cells. Eur J Biochem. 1997 May 15;246(1):45-9. [Content Brief]
