Nalanthalide
Nalanthalide is a voltage-gated potassium channel Kv1.3 blocker (IC50=3.9 µM) and a potential immunosuppressant. Nalanthalide can be used for research on inflammatory immune diseases, such as neuroinflammation.
For research use only. We do not sell to patients.
- CAS No.: 145603-76-5
- Formula: C30H44O5
- Molecular Weight:484.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 3.9 µM (Kv1.3)[1].
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| T-cell | EC50 |
500 nM
Compound: 7
|
Depolarization of human T cells by electrophysiological method
Depolarization of human T cells by electrophysiological method
|
[PMID: 19042133] |
Chemical Information
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CAS No. 145603-76-5
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Molecular Weight 484.67
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Formula C30H44O5
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SMILES
O=C1C(C[C@@H]2C(CC[C@@]3([H])[C@@](CC/C=C(C)/C)(C)[C@@H](OC(C)=O)CC[C@]23C)=C)=C(OC)OC(C)=C1C
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Structure Classification
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Initial Source
Nalanthamala sp.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)