12-Ethoxynimbolinin E
12-Ethoxynimbolinin E is a nimbolinin-type limonoid found in the fruits of Melia toosendan. 12-Ethoxynimbolinin E induces cytotoxic activity against cancer cells. 12-Ethoxynimbolinin E can be used for the research of cancer, such as myeloid leukemia, and lung cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1941147-56-3
- 分子式: C35H44O8
- 分子量:592.72
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
12-Ethoxynimbolinin E (Compound 1) inhibits viability of HL-60, A-549, MCF-7, and SW480 human tumor cell lines with IC50 values of 21.5, 26.4, 25.2, and 31.8 μM, respectively, and does not inhibit viability of SMMC-7721 cells at concentrations up to 40 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1941147-56-3
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分子量 592.72
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分子式 C35H44O8
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SMILES
C[C@]12[C@@]3([H])[C@](OC[C@@]3([C@@H](C[C@@H]2OC(C4=CC=CC=C4)=O)O)C)([H])[C@H]([C@@]5([C@]1([H])C[C@@H](O[C@]6([H])C5=C([C@H](C7=COC=C7)C6)C)OCC)C)O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)