IDO-IN-3
Based on 1 Customer Validation
IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.44%
- CAS 番号: 2070018-30-1
- 分子式: C11H12BrFN6O2
- 分子量:359.15
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
IC50 & Target
[1]|
IDO-1 290 nM (IC50) |
IDO 98 nM (IC50, in HeLa cell) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
98 nM
Compound: 4c
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Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrs
Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrs
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[PMID: 28523098] |
体外実験
化学情報
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CAS 番号 2070018-30-1
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性状 Solid
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分子量 359.15
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分子式 C11H12BrFN6O2
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Color White to off-white
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SMILES
O/N=C(NC1=CC(Br)=C(F)C=C1)\C2=NON=C2NCCN
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
溶剤 & 溶解度
体外:
DMSO : 27.5 mg/mL (76.57 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (282 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7844 mL | 13.9218 mL | 27.8435 mL | 69.6088 mL |
| 5 mM | 0.5569 mL | 2.7844 mL | 5.5687 mL | 13.9218 mL | |
| 10 mM | 0.2784 mL | 1.3922 mL | 2.7844 mL | 6.9609 mL | |
| 15 mM | 0.1856 mL | 0.9281 mL | 1.8562 mL | 4.6406 mL | |
| 20 mM | 0.1392 mL | 0.6961 mL | 1.3922 mL | 3.4804 mL | |
| 25 mM | 0.1114 mL | 0.5569 mL | 1.1137 mL | 2.7844 mL | |
| 30 mM | 0.0928 mL | 0.4641 mL | 0.9281 mL | 2.3203 mL | |
| 40 mM | 0.0696 mL | 0.3480 mL | 0.6961 mL | 1.7402 mL | |
| 50 mM | 0.0557 mL | 0.2784 mL | 0.5569 mL | 1.3922 mL | |
| 60 mM | 0.0464 mL | 0.2320 mL | 0.4641 mL | 1.1601 mL |
IDO-IN-3 関連分類
HY-16987 関連分類
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