Synaptic Vesicle Proteins Modulator
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SDI-118
0 ImagesSDI-118 is an orally active modulator for synaptic vesicle glycoprotein 2A (SV2A) with an IC50 of 13 nM.
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UCB1244283
0 ImagesUCB1244283 is an SV2A allosteric modulator. UCB1244283 stabilizes the closed SV2A conformation by binding to an intraluminal allosteric site, slows the dissociation of orthosteric ligands, and increases the affinity of Brivaracetam and the capacity of Levetiracetam (HY-B0106), and selectively binds SV2A rather than SV2B/SV2C through Leu655. UCB1244283 exhibits anticonvulsant activity, provides protection against tonic and clonic seizures, and can be used in epilepsy research.
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Seletracetam lithium bromide
0 Images製品番号: HY-119810BCAS 番号: 2024584-38-9別名: Ucb 44212 lithium bromideSeletracetam (Ucb 44212) lithium bromide, an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy.
