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製品番号: HY-U00313

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Tropodifene

(別名: Tropaphen)

Tropodifene (Tropaphen) is an α-Adrenergic receptor inhibitor.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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CAS 番号: 15790-02-0
分子式: C₂₅H₂₉NO₄
分子量:407.50

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Tropodifene 構造式

CAS 番号: 15790-02-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Tropodifene (Tropaphen) is an α-Adrenergic receptor inhibitor.

IC₅₀ & Target

α-Adrenergic^[1]

Adrenergic Receptor アイソフォーム固有の製品をすべて表示 :

体内実験

Tropaphen has a beneficial effect on hypertension. The therapeutic effect of this preparation is more constant in diseases accompanied by spasm of the peripheral vessels. Tropaphen has a very marked adrenolytic and vasodilator action. It greatly lowers the tone of the peripheral vessels. The preparation is effective starting with a dose of 0.1 mg/kg. After injection of the drug in a dose of 0.25 mg/kg, a considerable and gradually progressive decrease in the perfusion pressure takes place. The pressure falls by 30-35% and remained at a low level for 90-100 min. With a dose of tropaphen of 0.5 mg/kg, the perfusion pressure falls by 40-45% and remains low for 120 min or more. Strong vasodilatation is also observed after injection of tropaphen into intact rabbits^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 15790-02-0
分子量 407.50
分子式 C₂₅H₂₉NO₄
SMILES

O=C(O[C@H]1C[C@H](N2C)CC[C@H]2C1)C(C3=CC=CC=C3)CC4=CC=C(OC(C)=O)C=C4
別名

Tropaphen
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

プロトコル

Animal Administration^[1]

Rabbits^[1]

The drug is injected intravenously into rabbits. Experiments on the isolated ears of the rabbits are carried out by the Kravkov--Pisemskii method. The effect of tropaphen on the ear vessels of the intact rabbit is judged by the changes in the temperature of the ear. The temperature is measured by means of an electrothermometer, the detector of which is fixed to the internal surface of the ear. The dilation of the auricular vessels is also examined under the microscope, observations being made on the lumen of the marginal artery and vein^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (269 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Mashkovskii MD, et al. The action of tropaphen on the peripheral vessels. Pharmacology. 1964. 58. 69-71.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

希釈計算機

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濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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生物活性
- 製品説明
- IC₅₀ & Target
- 体内実験
化学情報
プロトコル
純度とドキュメンテーション
参考文献

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Tropodifene

Adrenergic Receptor アイソフォーム固有の製品をすべて表示