AB10
AB10 is a selective S1R antagonist. AB10 with Ki of 10, 165 nM for S1R and S2R, respectively. AB10 reverses the effect of Capsaicin (HY-10448) caused pain in model.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C23H30N2
- 分子量:334.50
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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Sigma 1 Receptor 10 nM (Ki) |
Sigma 2 Receptor 165 nM (Ki) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Capsaicin-induced as a pain model in CD1 mice[1]
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Dosage:20 mg/kg
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Administration:subcutaneous injection performed in different areas of the interscapular zone, administered 30 min before the injection of Capsaicin (HY-10448).
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Result:Achieved similar effects at half the concentration of BD-1063 (HY-18101A) (40mg/kg). Showed complete reversal of the mechanical hypersensitivity reaction.
化学情報
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分子量 334.50
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分子式 C23H30N2
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SMILES
C1(CN(CC2=CC=CC=C2)C3)C3CCCN1CCCC4=CC=CC=C4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
AB10 関連分類
HY-149855 関連分類
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