BETA-1
Based on 1 Customer Validation
BETA-1 is the first twisted intramolecular charge transfer (TICT)-aggregation-induced emission (AIE) integration molecule. BETA-1 emits cyan fluorescence in lipid droplets (LDs) and red fluorescence in mitochondria. BETA-1 can be used for the simultaneous and dual-color imaging of LDs and mitochondria in vivo and in vitro.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.42%
- CAS 番号: 2924598-24-1
- 分子式: C37H28IN3S2
- 分子量:705.67
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
製品説明
体外実験
Guide (The following is our recommended solution. This solution is merely a guideline and should be modified according to your specific needs.)
The HeLa cells were cultured in DMEM medium supplemented with 10% FBS, in a 37 °C CO?/air (5%/95%) incubator.
2. 5.0 × 103 HeLa cells were inoculated into each well of a 96-well glass-bottom plate and incubated for 24 hours.
3. For cell imaging, live HeLa cells were stained with 5 μM BETA-1 at 37 °C for 30 minutes.
4. Collect the emission light of BETA-1 under the excitation wavelengths of 405 or 561 nm. Record digital images using a laser scanning confocal microscope. Analyze the images using Fiji/ImageJ.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
臨床実験
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 2924598-24-1
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性状 Solid
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分子量 705.67
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分子式 C37H28IN3S2
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Color Brown to black
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SMILES
C[N+]1=C(/C=C/C2=CC=C(N(C3=CC=C(/C=C/C4=NC5=CC=CC=C5S4)C=C3)C6=CC=CC=C6)C=C2)SC7=CC=CC=C17.[I-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 25 mg/mL (35.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4171 mL | 7.0855 mL | 14.1709 mL | 35.4273 mL |
| 5 mM | 0.2834 mL | 1.4171 mL | 2.8342 mL | 7.0855 mL | |
| 10 mM | 0.1417 mL | 0.7085 mL | 1.4171 mL | 3.5427 mL | |
| 15 mM | 0.0945 mL | 0.4724 mL | 0.9447 mL | 2.3618 mL | |
| 20 mM | 0.0709 mL | 0.3543 mL | 0.7085 mL | 1.7714 mL | |
| 25 mM | 0.0567 mL | 0.2834 mL | 0.5668 mL | 1.4171 mL | |
| 30 mM | 0.0472 mL | 0.2362 mL | 0.4724 mL | 1.1809 mL |