BRD1554
BRD1554 is an inhibitor of the thioesterase domain of polyketide synthase 13 (Pks13) from Mycobacterium tuberculosis, and exhibits selective activity against Pks13-expressing strains. Pks13 is a polyketide synthase essential for the synthesis of branched-chain fatty acids in mycobacteria. BRD1554 serves as a scaffold molecule for anti-Mycobacterium tuberculosis agents. BRD1554 can be used in the research of tuberculosis.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C19H19FN4O3
- 分子量:370.38
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
BRD1554 (1-100 μM; 14 days) selectively hypersensitizes Pks13 and Rv2581c hypomorphic Mtb strains, with a maximal confidence PCL match to Pks13 inhibitors, indicating it targets the Pks13 thioesterase domain[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 370.38
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分子式 C19H19FN4O3
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SMILES
CC1=NOC(CC2COCC2NC(C3=CC(C4=CC=C(C=C4)F)=NN3)=O)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
BRD1554 関連分類
HY-183968 関連分類
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