CCZ01048 TFA
Based on 4 publication(s) in Google Scholar
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.54%
- 分子式: C73H106F3N21O18
- 分子量:1622.75
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 CCZ01048 TFA
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生物活性
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MC1R |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
DOTA-{4-amino-(1-carboxymethyl) piperidine (Pip)-Nle-CycMSHhex}
DOTA-{4-amino-(1-carboxymethyl) piperidine (Pip)-Nle-CycMSHhex}
化学情報
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性状 Solid
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分子量 1622.75
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分子式 C73H106F3N21O18
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Color White to off-white
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (4)
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Journal Impact Factor
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Most Recent
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Sci Rep
First-in-human dosimetry and safety evaluation of 68Ga-αMSH derivative for PET imaging of melanoma. [Abstract]2025 May 22;15(1):17748. PMID: 40404705 -
Bioconjug Chem
Radiolabeling Optimization and Preclinical Evaluation of the New PSMA Imaging Agent [18F]AlF-P16-093. [Abstract]2021 May 19;32(5):1017-1026. PMID: 33872489 -
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Iran J Immunol
Letter to the Editor Regarding "An Overview on Serology and Molecular Tests for COVID-19: An Important Challenge of the Current Century (doi: 10.22034/iji.2021.88660.1894.)". [Abstract]2022 Sep;19(3):337. PMID: 36190387
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (61.62 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
純度とドキュメンテーション
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データシート (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6162 mL | 3.0812 mL | 6.1624 mL | 15.4059 mL |
| 5 mM | 0.1232 mL | 0.6162 mL | 1.2325 mL | 3.0812 mL | |
| 10 mM | 0.0616 mL | 0.3081 mL | 0.6162 mL | 1.5406 mL | |
| 15 mM | 0.0411 mL | 0.2054 mL | 0.4108 mL | 1.0271 mL | |
| 20 mM | 0.0308 mL | 0.1541 mL | 0.3081 mL | 0.7703 mL | |
| 25 mM | 0.0246 mL | 0.1232 mL | 0.2465 mL | 0.6162 mL | |
| 30 mM | 0.0205 mL | 0.1027 mL | 0.2054 mL | 0.5135 mL | |
| 40 mM | 0.0154 mL | 0.0770 mL | 0.1541 mL | 0.3851 mL | |
| 50 mM | 0.0123 mL | 0.0616 mL | 0.1232 mL | 0.3081 mL | |
| 60 mM | 0.0103 mL | 0.0514 mL | 0.1027 mL | 0.2568 mL |
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