CDK2-IN-22
Based on 1 Customer Validation
CDK2-IN-22 (compound 7I) is a potent CDK2 inhibitor with an IC50 of 64.42 nM. CDK2-IN-22 presents a broad antiproliferative efficacy toward diverse cancer cells MV4-11, HT-29, MCF-7, and HeLa with IC50 values of 0.83 μM, 2.12 μM, 3.12 μM, and 8.61 μM, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.64%
- 分子式: C21H18N6O3S
- 分子量:434.47
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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CDK2 64.42 nM (IC50) |
化学情報
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性状 Solid
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分子量 434.47
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分子式 C21H18N6O3S
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Color White to off-white
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SMILES
O=S(C1=CC=C(NC2=NC=CC(NC3=CC(OC4=CC=CC=C4)=CN=C3)=N2)C=C1)(N)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 250 mg/mL (575.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.3017 mL | 11.5083 mL | 23.0165 mL | 57.5414 mL |
| 5 mM | 0.4603 mL | 2.3017 mL | 4.6033 mL | 11.5083 mL | |
| 10 mM | 0.2302 mL | 1.1508 mL | 2.3017 mL | 5.7541 mL | |
| 15 mM | 0.1534 mL | 0.7672 mL | 1.5344 mL | 3.8361 mL | |
| 20 mM | 0.1151 mL | 0.5754 mL | 1.1508 mL | 2.8771 mL | |
| 25 mM | 0.0921 mL | 0.4603 mL | 0.9207 mL | 2.3017 mL | |
| 30 mM | 0.0767 mL | 0.3836 mL | 0.7672 mL | 1.9180 mL | |
| 40 mM | 0.0575 mL | 0.2877 mL | 0.5754 mL | 1.4385 mL | |
| 50 mM | 0.0460 mL | 0.2302 mL | 0.4603 mL | 1.1508 mL | |
| 60 mM | 0.0384 mL | 0.1918 mL | 0.3836 mL | 0.9590 mL | |
| 80 mM | 0.0288 mL | 0.1439 mL | 0.2877 mL | 0.7193 mL | |
| 100 mM | 0.0230 mL | 0.1151 mL | 0.2302 mL | 0.5754 mL |
CDK2-IN-22 関連分類
HY-157516 関連分類
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