DM4-SMCC
Based on 1 Customer Validation
DM4-SMCC is a agent-linker conjugate for ADC with antitumor activity by using DM4 (an antitubulin agent), linked via the non-cleavable SMCC linker.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 96.86%
- CAS 番号: 1228105-52-9
- 分子式: C54H72ClN5O16S
- 分子量:1114.69
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Drug-Linker Conjugates for ADC アイソフォーム固有の製品をすべて表示
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生物活性
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Maytansinoids |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1228105-52-9
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性状 Solid
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分子量 1114.69
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分子式 C54H72ClN5O16S
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Color White to off-white
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SMILES
C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(CCC(C)(C)SC(C5)C(N(CC6CCC(C(ON7C(CCC7=O)=O)=O)CC6)C5=O)=O)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 125 mg/mL (112.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (420 KB)
- English - EN (420 KB)
- Français - FR (420 KB)
- Deutsch - DE (420 KB)
- Norwegian - NO (420 KB)
- Español - ES (420 KB)
- Swedish - SV (420 KB)
- Italian - IT (420 KB)
- Korean - KR (420 KB)
- Portuguese - PT (420 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8971 mL | 4.4856 mL | 8.9711 mL | 22.4278 mL |
| 5 mM | 0.1794 mL | 0.8971 mL | 1.7942 mL | 4.4856 mL | |
| 10 mM | 0.0897 mL | 0.4486 mL | 0.8971 mL | 2.2428 mL | |
| 15 mM | 0.0598 mL | 0.2990 mL | 0.5981 mL | 1.4952 mL | |
| 20 mM | 0.0449 mL | 0.2243 mL | 0.4486 mL | 1.1214 mL | |
| 25 mM | 0.0359 mL | 0.1794 mL | 0.3588 mL | 0.8971 mL | |
| 30 mM | 0.0299 mL | 0.1495 mL | 0.2990 mL | 0.7476 mL | |
| 40 mM | 0.0224 mL | 0.1121 mL | 0.2243 mL | 0.5607 mL | |
| 50 mM | 0.0179 mL | 0.0897 mL | 0.1794 mL | 0.4486 mL | |
| 60 mM | 0.0150 mL | 0.0748 mL | 0.1495 mL | 0.3738 mL | |
| 80 mM | 0.0112 mL | 0.0561 mL | 0.1121 mL | 0.2803 mL | |
| 100 mM | 0.0090 mL | 0.0449 mL | 0.0897 mL | 0.2243 mL |
DM4-SMCC 関連分類
HY-126494 関連分類
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