DMANI
Based on 1 Customer Validation
DMANI is an intramolecular charge transfer (ICT)-based mitochondria-targeted ratiometric fluorescent probe. DMANI can monitor mitochondrial peroxynitrite (ONOO−) in living cells.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.81%
- CAS 番号: 2978635-30-0
- 分子式: C25H27IN2
- 分子量:482.40
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
In PBS buffer (10 mM, pH = 7.4), the DMANI (5 μM) displays absorption bands at around 525 and 346 nm, but the addition of 30 μM ONOO− significantly decreased the absorption, together with the appearance of a new peak at about 360 nm. In the emission spectra, a remarkably decreased fluorescence was observed at 692 nm and a new emission band at 444 nm appeared and increased rapidly in the case of DMANI with ONOO−[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2978635-30-0
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性状 Solid
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分子量 482.40
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分子式 C25H27IN2
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Color Brown to black
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SMILES
CN(C)C1=CC=C2C(C=CC(/C=C/C(C3(C)C)=[N+](C)C4=C3C=CC=C4)=C2)=C1.[I-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
DMSO : 100 mg/mL (207.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0730 mL | 10.3648 mL | 20.7297 mL | 51.8242 mL |
| 5 mM | 0.4146 mL | 2.0730 mL | 4.1459 mL | 10.3648 mL | |
| 10 mM | 0.2073 mL | 1.0365 mL | 2.0730 mL | 5.1824 mL | |
| 15 mM | 0.1382 mL | 0.6910 mL | 1.3820 mL | 3.4549 mL | |
| 20 mM | 0.1036 mL | 0.5182 mL | 1.0365 mL | 2.5912 mL | |
| 25 mM | 0.0829 mL | 0.4146 mL | 0.8292 mL | 2.0730 mL | |
| 30 mM | 0.0691 mL | 0.3455 mL | 0.6910 mL | 1.7275 mL | |
| 40 mM | 0.0518 mL | 0.2591 mL | 0.5182 mL | 1.2956 mL | |
| 50 mM | 0.0415 mL | 0.2073 mL | 0.4146 mL | 1.0365 mL | |
| 60 mM | 0.0345 mL | 0.1727 mL | 0.3455 mL | 0.8637 mL | |
| 80 mM | 0.0259 mL | 0.1296 mL | 0.2591 mL | 0.6478 mL | |
| 100 mM | 0.0207 mL | 0.1036 mL | 0.2073 mL | 0.5182 mL |
DMANI 関連分類
HY-D2479 関連分類
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