Tle4 - TLE family member 4, transcriptional corepressor Gene

Also Known as Esp2; Grg-4

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 25565

Summary

Predicted to enable DNA-binding transcription factor binding activity; chromatin binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway; cellular response to leukemia inhibitory factor; and negative regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human TLE4 (TLE family member 4, transcriptional corepressor). [provided by Alliance of Genome Resources, Apr 2022]

Tle4 Products (2)

mRNA Protein Name
NM_001414041.1 NP_001400970.1 transducin-like enhancer protein 4 isoform 1
NM_019141.3 NP_062014.2 transducin-like enhancer protein 4 isoform 2
Protein Preferred Names Protein Names

transducin-like enhancer protein 4

  • groucho-related protein 4

  • transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)

  • transducin-like enhancer of split 4, E(spl) homolog

  • transducin-like enhancer of split 4, homolog of Drosophila E(spl)

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Tle4 NCBI NCBI:7091