RAI14 - retinoic acid induced 14 Gene

Also Known as RAI13; NORPEG

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 26064

About RAI14

Cytogenetic location: 5p13.2 Genomic coordinates (GRCh38): 5:34,656,328-34,832,612 (from NCBI)

This gene has 28 transcripts (splice variants) and 203 orthologues. Broad expression in endometrium (RPKM 27.5), placenta (RPKM 14.1) and 23 other tissues.

Summary

Predicted to enable actin binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of NIK/NF-kappaB signaling; and spermatogenesis. Located in cytosol; fibrillar center; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RAI14 Products (6)

mRNA	Protein	Name
NM_001145520.1	NP_001138992.1	ankycorbin isoform a
NM_001145521.2	NP_001138993.1	ankycorbin isoform a
NM_001145522.2	NP_001138994.1	ankycorbin isoform b
NM_001145523.2	NP_001138995.1	ankycorbin isoform c
NM_001145525.2	NP_001138997.1	ankycorbin isoform d
NM_015577.3	NP_056392.2	ankycorbin isoform a

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	参考文献	由来
enables protein binding	IPI IPI: Inferred from physical interaction	15161933	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RAI14 Protein Structure

Ank_2

0
200
400
600
800
980 a.a.

Protein Preferred Names	Protein Names
ankycorbin	ankyrin repeat and coiled-coil structure-containing protein

RAI14 Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	RAI14	Q9P0K7	YWHAZ	Homo sapiens	P63104	Pull Down	15161933

Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases	Alias
Cardiomyopathy, Infantile Histiocytoid	Histiocytoid Cardiomyopathy Foamy Myocardial Transformation Of Infancy Infantile Histiocytoid Cardiomyopathy Infantile Xanthomatous Cardiomyopathy Oncocytic Cardiomyopathy Cardiomyopathy, Infantile Xanthomatous Cardiomyopathy, Focal Lipid Cardiomyopathy, Oncocytic Focal Lipid Cardiomyopathy Infantile Cardiomyopathy With Histiocytoid Change CMIH Cardiomyopathy Focal Lipid Cardiomyopathy Infantile Xanthomatous Cardiomyopathy Oncocytic
Twin-To-Twin Transfusion Syndrome	Twin To Twin Transfusion Syndrome Twin Twin Transfusion Syndrome Fetal Blood Loss From Fetal Hemorrhage Into Co-Twin Fetal Hemorrhage Into Co-Twin Twin To Twin Transfusion Twin-To-Twin Blood Transfer Fetal Transfusion Syndrome Fetofetal Transfusion Syndrome Ttts Feto-Fetal Transfusion Syndrome Fetofetal Transfusion Fetus-To-Fetus Placental Transfusion Syndrome
Potocki-Lupski Syndrome	PTLS Chromosome 17p11.2 Duplication Syndrome 17p11.2 Microduplication Syndrome Duplication 17p11.2 Syndrome Trisomy 17p11.2 Potocki-Lupski Syndrome (Dup(17)(P11.2p11.2)) 17p11.2 Duplication Syndrome Dup(17)(P11.2p11.2) Pls Chromosome 17, Trisomy 17p11 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-RS11625	RAI14 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Canis familiaris	RAI14	VGNC	VGNC:45329
Felis catus	RAI14	VGNC	VGNC:64482
Bos taurus	RAI14	VGNC	VGNC:33696
Rattus norvegicus	RAI14	RGD	RGD:1305942
Mus musculus	RAI14	MGD	MGI:1922896
Macaca mulatta	RAI14	VGNC	VGNC:76478
Others	RAI14	NCBI