TRAPPC3 - trafficking protein particle complex subunit 3 Gene

Also Known as BET3

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 27095

About TRAPPC3

Cytogenetic location: 1p34.3 Genomic coordinates (GRCh38): 1:36,136,572-36,156,053 (from NCBI)

This gene has 10 transcripts (splice variants), 213 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 23.9), adrenal (RPKM 19.7) and 25 other tissues.

Summary

This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. The encoded protein participates in the regulation of transport from the endoplasmic reticulum to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

TRAPPC3 Products (5)

mRNA Protein Name
NM_001270894.2 NP_001257823.1 trafficking protein particle complex subunit 3 isoform 2
NM_001270895.2 NP_001257824.1 trafficking protein particle complex subunit 3 isoform 3
NM_001270896.2 NP_001257825.1 trafficking protein particle complex subunit 3 isoform 3
NM_001270897.2 NP_001257826.1 trafficking protein particle complex subunit 3 isoform 4
NM_014408.5 NP_055223.1 trafficking protein particle complex subunit 3 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
part of TRAPP complex IDA
IDA: Inferred from direct assay
21525244 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRAPPC3 Protein Structure

TRAPP

TRAPP: Transport protein particle (TRAPP) component (18 - 166)

  • 0
  • 100
  • 180 a.a.
Protein Preferred Names Protein Names

trafficking protein particle complex subunit 3

  • trafficking protein particle complex 3

TRAPPC3 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
TRAPPC3 O43617 TRAPPC2L Homo sapiens Q9UL33-2
Y2H Array
32296183
Intra
TRAPPC3 O43617 TRAPPC2L Homo sapiens Q9UL33-2
Validated Y2H
32296183
Intra
TRAPPC3 O43617 TRAPPC2L Homo sapiens Q9UL33-2
Y2H Prey Pooling
32296183
Intra
TRAPPC3 O43617 TRAPPC2 Homo sapiens P0DI81-3
Y2H Prey Pooling
32296183
Intra
TRAPPC3 O43617 TRAPPC2 Homo sapiens P0DI81-3
Validated Y2H
32296183
Intra
TRAPPC3 O43617 TRAPPC2 Homo sapiens P0DI81-3
Y2H Array
32296183
Intra
TRAPPC3 O43617 TRAPPC13 Homo sapiens A5PLN9
Anti Tag CoIP
21453443
Intra
TRAPPC3 O43617 TRAPPC5 Homo sapiens Q8IUR0
Y2H Prey Pooling
32296183
Intra
TRAPPC3 O43617 TRAPPC5 Homo sapiens Q8IUR0
Validated Y2H
32296183
Intra
TRAPPC3 O43617 TRAPPC5 Homo sapiens Q8IUR0
Y2H Array
32296183
Intra
TRAPPC3 O43617 TRAPPC6B Homo sapiens Q86SZ2
Anti Bait CoIP
18930054
Intra
TRAPPC3 O43617 TRAPPC6B Homo sapiens Q86SZ2
Anti Tag CoIP
16908848
Intra
TRAPPC3 O43617 TRAPPC1 Homo sapiens Q9Y5R8
Y2H Array
32296183
Intra
TRAPPC3 O43617 TRAPPC1 Homo sapiens Q9Y5R8
Y2H Prey Pooling
32296183
Intra
TRAPPC3 O43617 TRAPPC1 Homo sapiens Q9Y5R8
Validated Y2H
32296183
Intra
TRAPPC3 O43617 PLEKHF2 Homo sapiens Q9H8W4
Y2H Array
25416956
Intra
TRAPPC3 O43617 PLEKHF2 Homo sapiens Q9H8W4
Validated Y2H
25416956
Intra
TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865
Y2H Pooling
16189514
Intra
TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865
Y2H Prey Pooling
25416956
Intra
TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865
Validated Y2H
25416956
Intra
TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865
Y2H Array
25416956
Intra
TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865
Anti Bait CoIP
18930054
Intra
TRAPPC3 O43617 TRAPPC2L Homo sapiens Q9UL33
Y2H Pooling
16189514
Intra
TRAPPC3 O43617 TRAPPC2L Homo sapiens Q9UL33
Y2H Prey Pooling
25416956
Intra
TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865-2
Anti Bait CoIP
18930054
Intra
TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865-2
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Spondyloepiphyseal Dysplasia Tarda, X-Linked

  • Spondyloepiphyseal Dysplasia Tarda

  • X-Linked Spondyloepiphyseal Dysplasia Tarda

  • SEDT

  • Sed Tarda, X-Linked

  • Spondyloepiphyseal Dysplasia, Late

  • Spondyloepiphyseal Dysplasia Tarda X-Linked

  • Sed

  • X Linked Spondyloepiphyseal Dysplasia Tarda

  • X-Linked Spondyloepiphyseal Dysplasia

  • Late Onset Spondyloepiphyseal Dysplasia

  • Sed Tarda

  • X-Linked Sed

  • X-Linked Sedt

  • Dysplasia, Spondyloepiphyseal, Tarda

  • Spondyloepiphyseal Dysplasia
Bardet-Biedl Syndrome

  • Bbs

  • Biedl-Bardet Syndrome
Celery Allergy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS14990 TRAPPC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus TRAPPC3 RGD RGD:1309135
Mus musculus TRAPPC3 MGD MGI:1351486
Felis catus TRAPPC3 VGNC VGNC:107683
Canis familiaris TRAPPC3 VGNC VGNC:47781
Macaca mulatta TRAPPC3 VGNC VGNC:79210
Bos taurus TRAPPC3 VGNC VGNC:36288
Others TRAPPC3 NCBI