NIT1 - nitrilase 1 Gene

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 4817

About NIT1

Cytogenetic location: 1q23.3 Genomic coordinates (GRCh38): 1:161,118,105-161,125,445 (from NCBI)

This gene has 16 transcripts (splice variants), 195 orthologues and 2 paralogues. Ubiquitous expression in adrenal (RPKM 11.4), kidney (RPKM 10.4) and 25 other tissues.

Summary

This gene encodes a member of the nitrilase protein family with homology to Bacterial and plant nitrilases, Enzymes that cleave nitriles and organic amides to the corresponding carboxylic acids plus ammonia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

NIT1 Products (4)

mRNA Protein Name
NM_001185092.2 NP_001172021.1 deaminated glutathione amidase isoform 2
NM_001185093.2 NP_001172022.1 deaminated glutathione amidase isoform 3
NM_001185094.2 NP_001172023.1 deaminated glutathione amidase isoform 4
NM_005600.3 NP_005591.1 deaminated glutathione amidase isoform 1

NIT1 Protein Structure

CN_hydrolase

CN_hydrolase: Carbon-nitrogen hydrolase (48 - 228)

  • 0
  • 100
  • 200
  • 300
  • 327 a.a.
Protein Preferred Names Protein Names

deaminated glutathione amidase

  • dGSH amidase

NIT1 抗体

製品番号 製品名 アプリケーション 反応性
HY-P81656 NIT1 Antibody (YA1401) WB, IP Human, Mouse, Rat
HY-P81656A NIT1 Antibody (YA1401)(PBS only) WB, IP Human, Mouse, Rat

関連疾患

Diseases Alias
Pancreatic Cystadenoma

  • Cystadenoma Of Pancreas
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-P10622 SHLP-3 Inhibitor / Unkown
HY-P10625 SHLP-6 / Unkown
HY-RS09310 NIT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19359 Nit1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25851 Nit1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Macaca mulatta NIT1 VGNC VGNC:75351
Rattus norvegicus NIT1 RGD RGD:727821
Felis catus NIT1 VGNC VGNC:107904
Canis familiaris NIT1 VGNC VGNC:53123
Bos taurus NIT1 VGNC VGNC:32089
Mus musculus NIT1 MGD MGI:1350916
Others NIT1 NCBI