MOB3B - MOB kinase activator 3B Gene

Also Known as MOB1D; C9orf35; MOBKL2B

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 79817

About MOB3B

Cytogenetic location: 9p21.2 Genomic coordinates (GRCh38): 9:27,325,209-27,529,814 (from NCBI)

This gene has 2 transcripts (splice variants), 150 orthologues and 6 paralogues. Ubiquitous expression in ovary (RPKM 14.2), duodenum (RPKM 9.8) and 20 other tissues.

Summary

The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene. [provided by RefSeq, Jul 2008]

MOB3B Products (1)

mRNA Protein Name
NM_024761.5 NP_079037.3 MOB kinase activator 3B

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in regulation of hippo signaling IMP
IMP: Inferred from mutant phenotype
28792927 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MOB3B Protein Structure

Mob1_phocein

Mob1_phocein: Mob1/phocein family (31 - 208)

  • 0
  • 100
  • 200
  • 216 a.a.
Protein Preferred Names Protein Names

MOB kinase activator 3B

  • MOB kinase activator-like 2B

関連疾患

Diseases Alias
Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1

  • FTDALS1

  • Frontotemporal Dementia And/Or Motor Neuron Disease

  • Ftdmnd

  • Amyotrophic Lateral Sclerosis And/Or Frontotemporal Dementia

  • Alsftd

  • Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis

  • Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis-1

  • Frontotemporal Dementia With Motor Neuron Disease

  • Ftdals

  • Ftd-Als

  • Ftd-Mnd

  • Frontotemporal Dementia With Amyotrophic Lateral Sclerosis

  • Amyotrophic Lateral Sclerosis With Frontotemporal Dementia 1

  • Amyotrophic Lateral Sclerosis/Frontotemporal Dementia

  • Dementia, Frontotemporal, And/Or Amyotrophic Lateral Sclerosis

  • Amyotrophic Lateral Sclerosis And/Or Frontotemporal Dementia 1

  • Frontotemporal Lobar Degeneration

  • Grn-Related Frontotemporal Dementia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS08576 MOB3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Canis familiaris MOB3B VGNC VGNC:43303
Felis catus MOB3B VGNC VGNC:63547
Mus musculus MOB3B MGD MGI:2664539
Rattus norvegicus MOB3B RGD RGD:1560696
Bos taurus MOB3B VGNC VGNC:31545
Others MOB3B NCBI