NRIP2 - nuclear receptor interacting protein 2 Gene

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 83714

About NRIP2

This gene has 3 transcripts (splice variants), 174 orthologues and 4 paralogues. Ubiquitous expression in kidney (RPKM 4.3), ovary (RPKM 4.3) and 25 other tissues.

Summary

Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within Notch signaling pathway and negative regulation of transcription by RNA polymerase II. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

NRIP2 Products (1)

mRNA Protein Name
NM_031474.3 NP_113662.1 nuclear receptor-interacting protein 2

NRIP2 Protein Structure

Asp_protease

Asp_protease: Aspartyl protease (156 - 255)

  • 0
  • 100
  • 200
  • 281 a.a.
Protein Preferred Names Protein Names

nuclear receptor-interacting protein 2

NRIP2 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
NRIP2 Q9BQI9 BANP Homo sapiens Q8N9N5-2
Y2H Prey Pooling
32296183
Intra
NRIP2 Q9BQI9 BANP Homo sapiens Q8N9N5-2
Y2H Array
32296183
Intra
NRIP2 Q9BQI9 HDAC7 Homo sapiens Q8WUI4-6
Y2H Prey Pooling
32296183
Intra
NRIP2 Q9BQI9 HDAC7 Homo sapiens Q8WUI4-6
Y2H Array
32296183
Intra
NRIP2 Q9BQI9 HDAC7 Homo sapiens Q8WUI4-6
MAPPIT
32296183
Intra
NRIP2 Q9BQI9 BANP Homo sapiens Q8N9N5
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Temtamy Syndrome

  • TEMTYS

  • Craniofacial Dysmorphism With Ocular Coloboma Absent Corpus Callosum And Aortic Dilatation

  • Craniofacial Dysmorphism-Coloboma-Corpus Callosum Agenesis Syndrome

  • Dysmorphism, Corpus Callosum Agenesis And Colobomas

  • Temtamy-Shalash Syndrome

  • Mental Retardation With Or Without Craniofacial Dysmorphism, Ocular Coloboma, Or Abnormal Corpus Callosum
Sneddon Syndrome

  • Livedo Reticularis And Cerebrovascular Accidents

  • SNDNS

  • Ehrmann-Sneddon Syndrome

  • Livedo Racemosa-Cerebrovascular Accident Syndrome

  • Livedo Reticularis-Cerebrovascular Accident Syndrome

  • Sneddon'S Syndrome

  • Idiopathic Livedo Reticularis With Systemic Involvement

  • Cerebro-Vascular Lesions And Livedo Reticularis

  • Livedo Racemosa And Cerebrovascular Accidents
Cantu Syndrome

  • Hypertrichotic Osteochondrodysplasia

  • Hypertrichotic Osteochondrodysplasia Cantu Type

  • Cantú Syndrome

  • Craniofaciocardioskeletal Syndrome

  • Hypertrichosis-Osteochondrodysplasia-Cardiomegaly Syndrome

  • Congenital Hypertrichosis-Acromegaloid Facial Features Spectrum

  • Congenital Hypertrichosis-Coarse Facial Features Spectrum

  • HTOCD

  • Osteochondrodysplasia, Hypertrichotic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS09572 NRIP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus NRIP2 RGD RGD:1589959
Felis catus NRIP2 VGNC VGNC:63879
Bos taurus NRIP2 VGNC VGNC:59356
Macaca mulatta NRIP2 VGNC VGNC:75448
Mus musculus NRIP2 MGD MGI:1891884
Canis familiaris NRIP2 VGNC VGNC:43970
Others NRIP2 NCBI