LTV1 - LTV1 ribosome biogenesis factor Gene

Also Known as C6orf93; dJ468K18.4

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 84946

About LTV1

Cytogenetic location: 6q24.2 Genomic coordinates (GRCh38): 6:143,843,338-143,863,812 (from NCBI)

This gene has 1 transcript (splice variant) and 211 orthologues. Ubiquitous expression in bone marrow (RPKM 17.0), testis (RPKM 13.5) and 25 other tissues.

Summary

Predicted to be involved in ribosomal small subunit biogenesis and ribosomal small subunit export from nucleus. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

LTV1 Products (2)

mRNA Protein Name
NM_001329953.2 NP_001316882.1 protein LTV1 homolog isoform 2
NM_032860.5 NP_116249.2 protein LTV1 homolog isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
22113938 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LTV1 Protein Structure

LTV

LTV: Low temperature viability protein (11 - 449)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 475 a.a.
Protein Preferred Names Protein Names

protein LTV1 homolog

  • LTV1 homolog

LTV1 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
LTV1 Q96GA3 BYSL Homo sapiens Q13895
Anti Tag CoIP
35271311
Intra
LTV1 Q96GA3 BYSL Homo sapiens Q13895
Y2H Array
25416956
Intra
LTV1 Q96GA3 BYSL Homo sapiens Q13895
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Eumycotic Mycetoma

  • Eumycetoma

  • Maduromycosis

  • Mycetoma

  • Madura Foot

  • Maduromycosis, Mycotic

  • Mycotic Mycetoma

  • Mycetoma Of Foot

  • Eumycotic Maduromycosis

  • Mycetoma Due To Fungal Infection
Dermatomycosis

  • Dermatomycoses
Cauda Equina Syndrome

  • Cauda Equina

  • Polyradiculopathy
Diamond-Blackfan Anemia

  • Congenital Pure Red Cell Aplasia

  • Aase Syndrome

  • Erythrogenesis Imperfecta

  • Anemia, Diamond-Blackfan

  • Congenital Hypoplastic Anemia

  • Aase-Smith Ii Syndrome

  • Bds

  • Blackfan-Diamond Anemia

  • Congenital Prca

  • Congenital Hypoplastic Anemia, Blackfan-Diamond Type

  • Dba

  • Blackfan - Diamond Syndrome

  • Chronic Constitutional Pure Red Cell Anaemia

  • Anemia Diamond Blackfan Type

  • Anemia Congenital Erythroid Hypoplastic

  • Aregenerative Anemia Chronic Congenital

  • Blackfan Diamond Syndrome

  • Red Cell Aplasia, Pure Hereditary

  • Aase-Smith Syndrome Ii

  • Bda

  • Blackfan Diamond Anemia

  • Blackfan-Diamond Disease

  • Blackfan-Diamond Syndrome

  • Chronic Congenital Agenerative Anemia

  • Congenital Erythroid Hypoplastic Anemia

  • Congenital Hypoplastic Anemia Of Blackfan And Diamond

  • Congenital Pure Red Cell Anemia

  • Hypoplastic Congenital Anemia

  • Inherited Erythroblastopenia

  • Pure Hereditary Red Cell Aplasia

  • Anemia, Hypoplastic, Congenital

  • Anemia Hypoplastic Congenital

  • Fanconi Anemia

  • Constitutional Aplastic Anemia

  • Diamond-Blackfan Anemia 1

  • Aase Smith Syndrome 2

  • Congenital Red Cell Aplasia

  • Red Cell Aplasia Of Infants

  • Pure Red Cell Aplasia Of Infants

  • Congenital Red Cell Aplastic Anaemia

  • Congenital Pure Red Cell Anaemia

  • Congenital Erythroid Hypoplasia

  • Pearson Marrow-Pancreas Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-18667 LTV-1 Inhibitor 98.0% Unkown
HY-RS07887 LTV1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19914 Ltv1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26415 Ltv1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Felis catus LTV1 VGNC VGNC:102453
Macaca mulatta LTV1 VGNC VGNC:83430
Mus musculus LTV1 MGD MGI:2447810
Rattus norvegicus LTV1 RGD RGD:1311264
Others LTV1 NCBI