country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-153517

Copy Link Print Information

hRVs-IN-1

hRVs-IN-1 (Compound 6g) is a selective anti-hRV viral agent. hRVs-IN-1 inhibits the replication of tested hRV strains with EC₅₀ values of 0.083, 0.078, and 0.015 μM against hRV-B14, hRV-A21, and hRV-A71, respectively. hRVs-IN-1 inhibits the replication of PV3 with an EC₅₀ of 0.063 μM.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 2104030-01-3
分子式: C₂₀H₂₀N₂O₄S
分子量:384.45

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

hRVs-IN-1 構造式

CAS 番号: 2104030-01-3

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
H1-HeLa	CC₅₀	18.1 μM Compound: 6g	Cytotoxicity against human H1HeLa cells assessed as decrease in cell viability after 3 days by MTT assay Cytotoxicity against human H1HeLa cells assessed as decrease in cell viability after 3 days by MTT assay	[PMID: 28581749]
HeLa	CC₅₀	9.6 μM Compound: 6g	Cytotoxicity aganist human HeLa cells assessed as decrease in cell viability after 2 days by MTT assay Cytotoxicity aganist human HeLa cells assessed as decrease in cell viability after 2 days by MTT assay	[PMID: 28581749]
HeLa	EC₅₀	0.063 μM Compound: 6g	Antiviral activity against Human poliovirus 3 infected in human HeLa cells assessed as protection against virus induced cytopathic effect after 2 days by MTT assay Antiviral activity against Human poliovirus 3 infected in human HeLa cells assessed as protection against virus induced cytopathic effect after 2 days by MTT assay	[PMID: 28581749]

体外実験

hRVs-IN-1 (3 days) potently inhibits replication of hRV-B14, hRV-A21, and hRV-A71 in H1HeLa cells with EC₅₀ values of 0.083, 0.078, and 0.015 μM, respectively, and high selectivity indices ranging from 220 to 1200^[1].
hRVs-IN-1 (2 days) potently inhibits replication of PV3 in HeLa cells with an EC₅₀ of 0.063 μM and a selectivity index of 150^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 2104030-01-3
分子量 384.45
分子式 C₂₀H₂₀N₂O₄S
SMILES

O=C(OC(C)C)C=1SC=2C=C(OC=3C=CN=C(C3)C(=O)NC)C=CC2C1C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Kim J, et al. A Novel Series of Highly Potent Small Molecule Inhibitors of Rhinovirus Replication. J Med Chem. 2017;60(13):5472-5492. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

お問い合わせ在庫あり