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製品番号: HY-158741

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IPG-2 AM

Name: IPG-2 AM
Brand: MedChemExpress
SKU: HY-158741
Price: 1500.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(別名: APG-2 Acetoxymethyl ester)

カスタマーレビュー

Based on 1 Customer Validation

IPG-2 AM (APG-2 Acetoxymethyl ester) is a membrane-permeant acetoxymethyl ester derivative and selective fluorescent potassium ion indicator. IPG-2 AM exhibits fluorescence increases proportional to extracellular potassium ion concentrations. IPG-2 AM enables real-time monitoring of cytosolic free potassium ion fluxes in human platelets and macrophages. IPG-2 AM can be used for the research of intracellular potassium concentration dynamics.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

純度: 94.00%
CAS 番号: 1369302-24-8
分子式: C₅₅H₆₄Cl₂N₂O₁₉
分子量:1128.00

保管条件:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

IPG-2 AM 構造式

CAS 番号: 1369302-24-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

IPG-2 AM (1 μM; 10 min at 37°C) enables quantitative detection of intracellular potassium concentration changes in J774A.1 macrophages and BMDMs exposed to nsPEFs, and can detect immediate potassium efflux and subsequent recovery processes in most treated cell populations^[1].
Real-time flow cytometry analysis monitors cytoplasmic potassium efflux in human platelets treated with IPG-2 AM (0.1 μM; 60 min)^[2].
IPG-2 AM (0.1 μM; 60 min) exhibits an apparent K_d of 31 mM in human platelets, which validates its suitability for the quantitative detection of cytoplasmic potassium concentrations^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 1369302-24-8
性状 Solid
分子量 1128.00
分子式 C₅₅H₆₄Cl₂N₂O₁₉
SMILES

O=C(C)OCOC(CCC1=CC2=C(C3=CC(OC)=C(N4CCOCCOCCN(CCOCCOCC4)C5=CC=C(C)C=C5OC)C=C3)C6=C(C(Cl)=C(C(CCC(OCOC(C)=O)=O)=C6)OCOC(C)=O)OC2=C(C1=O)Cl)=O
別名

APG-2 Acetoxymethyl ester
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (274 KB)
SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Mazzarda F, et al. Inflammasome activation and IL-1β release triggered by nanosecond pulsed electric fields in murine innate immune cells and skin. The Journal of Immunology. 2024 Jan;212(2):335-45.

[2]. Aliotta A, et al. Flow Cytometric Monitoring of Dynamic Cytosolic Calcium, Sodium, and Potassium Fluxes Following Platelet Activation. Cytometry A. 2020;97(9):933-944. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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