JTP 2942
JTP 2942 is a thyrotropin-releasing hormone analogue. JTP 2942 can promote the release of Acetylcholine in the hippocampus and frontal cortex of rats. JTP 2942 possesses neuroprotective and cognitive-improving activities. JTP 2942 dose-dependently improves motor and neurological deficits in rat models of chronic focal cerebral ischemia. JTP 2942 can be used for the research of cerebral ischemia, motor neuron diseases, and other related conditions.
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- CAS 番号: 148152-77-6
- 分子式: C18H25N5O4
- 分子量:375.42
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
化学情報
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CAS 番号 148152-77-6
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分子量 375.42
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分子式 C18H25N5O4
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SMILES
O=C([C@@H]1[C@@H](CC(C1)=O)C)N[C@@H](CC2=CN=CN2)C(N3[C@@H](CCC3)C(N)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Yonemori F, et al. Effect of JTP-2942, a novel thyrotropin-releasing hormone analog, on motor deficits after chronic focal cerebral ischemia in rats. J Cereb Blood Flow Metab. 2000 Jan;20(1):74-81. [Content Brief]
[2]. Ikeda K, et al. JTP-2942, a novel thyrotropin-releasing hormone analogue, protects against spinal motor neuron degeneration in the wobbler mouse. Neurosci Lett. 1998 Jun 26;250(1):9-12. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)