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United States

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製品番号: HY-126825

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NE21650

NE21650 potently inhibits farnesyl diphosphate (FPP) synthase. NE21650 is a weak inhibitor of isopentenyl diphosphate (IPP) isomerase. NE21650 is a potent inhibitor of protein prenylation in osteoclasts and macrophages and bone resorption in vitro.

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CAS 番号: 427899-21-6
分子式: C₈H₁₃NO₇P₂
分子量:297.14

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

NE21650 構造式

CAS 番号: 427899-21-6

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	IC₅₀	205 μM Compound: 27	Toxicity against human MCF7 cells assessed as growth inhibition by broth microdilution method Toxicity against human MCF7 cells assessed as growth inhibition by broth microdilution method	[PMID: 18789701]
NCI-H460	IC₅₀	187 μM Compound: 27	Toxicity against human NCI-H460 cells assessed as growth inhibition by broth microdilution method Toxicity against human NCI-H460 cells assessed as growth inhibition by broth microdilution method	[PMID: 18789701]
SF-268	IC₅₀	186 μM Compound: 27	Toxicity against human SF268 cells assessed as growth inhibition by broth microdilution method Toxicity against human SF268 cells assessed as growth inhibition by broth microdilution method	[PMID: 18789701]

化学情報

CAS 番号 427899-21-6
分子量 297.14
分子式 C₈H₁₃NO₇P₂
SMILES

OC(P(O)(O)=O)(P(O)(O)=O)CC1=CC=CC=C1N
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (274 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Keith Thompson, et al. Identification of a bisphosphonate that inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase. Biochem Biophys Res Commun. 2002 Jan 18;290(2):869-73. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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