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NMT-IN-8

NMT-IN-8 (Compound Ex.129) is an orally active and highly selective inhibitor of N-myristoyl transferase (NMT) with an IC50 value of ＜10 nM. NMT-IN-8 binds to the peptide binding pocket of NMT, blocking its catalyzed protein N-myristoylation to interfere with key pathways such as protein trafficking, signal transduction, and viral replication. NMT-IN-8 is promising for research of oncology (e.g., MYC-addicted cancers, B-cell lymphoma) and infectious diseases (e.g., malaria, HIV, rhinovirus infection).

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  • CAS 番号: 2765258-26-0
  • 分子式: C23H29ClN8O
  • 分子量:468.98
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • NMT-IN-8 Chemical Structure
    NMT-IN-8 構造式
CAS 番号: 2765258-26-0
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  • NMT-IN-8 Chemical Structure
    NMT-IN-8 Chemical Structure
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  • NMT-IN-8