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製品番号: HY-116158

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Oosponol

Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.Oospongol has strong antifungal activity against many antagonistic fungi.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 146-04-3
分子式: C₁₁H₈O₅
分子量:220.18

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Oosponol 構造式

CAS 番号: 146-04-3

容量

価格（税別）

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数量

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.Oospongol has strong antifungal activity against many antagonistic fungi^[1]^[2].

体内実験

Oosponol (6.25 mg/kg, 3.1 mg/kg, ip, Once) can lower blood pressure in spontaneously hypertensive rats model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Spontaneously hypertensive rats^[1]
Dosage:

6.25 mg/kg, 3.1 mg/kg
Administration:

Intraperitoneal injection, once.
Result:

The intraperitoneal injection of 6.25 mg/kg lowered the pressure from 186 mm to 138~112 mm, the intraperitoneal injection of 3.1 mg/kg lowered the pressure from 185 mm to 164~131 mm^[1].

Animal Model:

Spontaneously hypertensive rats^[1]
Dosage:

6.25 mg/kg, 3.1 mg/kg
Administration:

Intraperitoneal injection, once.
Result:

The intraperitoneal injection of 6.25 mg/kg lowered the pressure from 186 mm to 138~112 mm, the intraperitoneal injection of 3.1 mg/kg lowered the pressure from 185 mm to 164~131 mm.

化学情報

CAS 番号 146-04-3
分子量 220.18
分子式 C₁₁H₈O₅
SMILES

O=C1OC=C(C2=C1C(O)=CC=C2)C(CO)=O
Structure Classification
- Phenols
- Monophenols
Initial Source
- Microorganisms
Gloeophyllum abietinum
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (270 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Umezawa H, et al.. Dopamine -hydroxylase inhibitor produced by Gloeophyllum striatum and its identity with oosponol. J Antibiot (Tokyo). 1972 Apr;25(4):239-42. [Content Brief]

[2]. Sonnenbichler J,et al. Influence of the Gloeophyllum metabolite oosponol and some synthetic analogues on protein and RNA synthesis in target cells. Eur J Biochem. 1997 May 15;246(1):45-9. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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希釈計算機

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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