Policresulen
Based on 1 Customer Validation
Policresulen is a competitive inhibitor for DENV2 NS2B/NS3 protease with an IC50 of 0.48 μg/mL. Policresulen can be used as a local hemostatic and antibacterial agent for research of cervical and vaginal inflammation, skin lesions, oral mucosa and gingival inflammation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 51.60%
- CAS 番号: 101418-00-2
- 分子式: (C8H10O4S)n
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
生物活性
Policresulen inhibits the DENV2 replication in cell BHK-21 with an IC50 of 4.99 μg/mL. Policresulen exhibits mild cytotoxicity in cell BHK-21 with an IC50 of 459.45 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Guinea pig models[2]
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Dosage:360 mg/kg
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Administration:topical application to the cheek pouch mucosa, twice daily for 15 days
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Result:Decreased the level of E-cadherin, caused histological changes including epithelial hyperplasia, vesicular degeneration, and abnormal mitosis.
化学情報
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CAS 番号 101418-00-2
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性状 Liquid
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分子式 (C8H10O4S)n
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Color Brown to orange
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SMILES
CC1=C(C)C(O)=C(S(=O)(O)=O)C=C1CC.[n]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
H2O : 100 mg/mL (Need ultrasonic)
DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)