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United States

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製品番号: HY-123184

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S 1924

S 1924 is a potent H+, K+-ATPase inhibitor, with IC₅₀ values of 10.3 and 1.6 μM at pH 7.4 and pH 6.0, respectively.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 111371-30-3
分子式: C₁₂H₁₁N₃OS₂
分子量:277.37

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

S 1924 構造式

CAS 番号: 111371-30-3

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

S 1924 is a potent H+, K+-ATPase inhibitor, with IC₅₀ values of 10.3 and 1.6 μM at pH 7.4 and pH 6.0, respectively^[1].

体外実験

S 1924 inhibits the histamine (HY-B1204)- and dbc-AMP (HY-B0764)-stimulated ¹⁴C-aminopyrine uptake^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

S 1924 (0.5 mg/kg, iv) inhibits desglugastrin (100 μg/kg/h, iv)-stimulated gastric acid secretion in stomach-lumen-perfused rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 111371-30-3
分子量 277.37
分子式 C₁₂H₁₁N₃OS₂
SMILES

O=S(CC1=NC=C(C=C1)C)C2=NC3=CSC=C3N2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (266 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Herling AW, et al. A substituted thieno[3.4-d]imidazole versus substituted benzimidazoles as H+, K+-ATPase inhibitors. Pharmacology. 1988;36(5):289-97. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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