(S)-HTS-3
(S)-HTS-3 is a Lysophosphatidylcholine acyltransferase 3 (LPCAT3/MBOAT5) inhibitor with a human IC50 of 4.1 μM. (S)-HTS-3 inhibits the acyltransferase activity of LPCAT3. (S)-HTS-3 modestly reduces incorporation of deuterated arachidonic acid into C20:4 phosphatidylserine in myeloid leukemia cells.
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- CAS 番号: 2771208-82-1
- 分子式: C17H18F2N2O
- 分子量:304.33
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
(S)-HTS-3 weakly inhibits recombinant human LPCAT3 in membrane lysates from HEK293T cells with an IC50 of 4.1 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2771208-82-1
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分子量 304.33
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分子式 C17H18F2N2O
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SMILES
O=C(C1=CC(F)=CC(F)=C1)NC[C@H](C2=CC=CC=C2)N(C)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)