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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
NMB-R
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "NMB-R" in MCE Product Catalog:
1
1 Cited Publications
製品番号: HY-103277A
純度: 96.20%
Target:
Target:
研究分野:
Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K + channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .
Target:
研究分野:
PD 168368 is a potent, competitive, and selective neuromedin B receptor (NMB-R) antagonist with the Ki of 15–45 nM . PD 168368 is neuromedin B receptor (NMBR; IC50=96 nM) / gastrin-releasing peptide receptor (GRPR IC50=3500 nM) antagonist . PD 168368 also is a mixed FPR1/FPR2/FPR3 agonist with EC50s of 0.57, 0.24, and 2.7 nM, respectively .
製品番号: HY-N2600
CAS 番号: 76472-87-2
製品番号: HY-P1423A
Target:
研究分野:
製品番号: HY-103277
CAS 番号: 111857-96-6
Target:
製品番号: HY-RS09369
Target:
研究分野:
NMBR Human Pre-designed siRNA Set A contains three designed siRNAs for NMBR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-P1423
CAS 番号: 183241-31-8
Target:
研究分野:
製品番号: HY-RS24284
Target:
研究分野:
Nmbr Rat Pre-designed siRNA Set A contains three designed siRNAs for Nmbr gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-N2600R
CAS 番号: 76472-87-2
製品番号: HY-RS17815
Target:
研究分野:
Nmbr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nmbr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-122351
CAS 番号: 245650-17-3
Target:
研究分野:
Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K + channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .
製品番号: HY-122351AR
CAS 番号: 714229-20-6
Target:
研究分野:
Advantame (Standard) is the analytical standard of Advantame. This product is intended for research and analytical applications. Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K + channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
