SNAP-6201
SNAP-6201 is a selective α1a adrenoceptor antagonist with a Ki of 0.2 nM. SNAP-6201 exhibits >1400-fold selectivity over α1b and α1d adrenoceptors. SNAP-6201 exhibits excellent selectively to inhibit intraurethral pressure (IUP) in the anesthetized dog model. SNAP-6201 can be used for benign prostatic hyperplasia (BPH) research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 252201-38-0
- 分子式: C30H35F2N5O5
- 分子量:583.63
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Adrenergic Receptor アイソフォーム固有の製品をすべて表示
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生物活性
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α1A-adrenergic receptor 0.2 nM (Ki) |
α1B-adrenergic receptor 260 nM (Ki) |
α1D-adrenergic receptor 350 nM (Ki) |
rat α1A-adrenergic receptor 0.27 nM (Ki) |
SNAP-6201 (compound 103) shows comparable binding affinity at the recombinant rat, dog, and human α1a adrenoceptors, with Kis of 0.3, 1.3, and 0.2 nM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 252201-38-0
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分子量 583.63
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分子式 C30H35F2N5O5
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SMILES
COC(C1(C2=CC=CC=C2)CCN(CCCNC(N3C(NC(CC)=C(C(N)=O)C3C4=CC(F)=C(F)C=C4)=O)=O)CC1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
SNAP-6201 関連分類
HY-W724254 関連分類
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