STING agonist-7
Based on 1 Customer Validation
STING agonist-7 is a non-nucleotide STING agonist. STING agonist-7 binds selectively to mouse STING but not human STING. STING agonist-7 penetrates cell membrane poorly.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.22%
- CAS 番号: 2767442-46-4
- 分子式: C17H12N4O4
- 分子量:336.30
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| H69AR | EC50 |
>100 μM
Compound: 11
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Agonist activity at STING in human THP1 Dual cells assessed as IRF reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay
Agonist activity at STING in human THP1 Dual cells assessed as IRF reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay
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[PMID: 35108011] |
| H69AR | EC50 |
>100 μM
Compound: 11
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Agonist activity at STING in human THP1-Dual cells assessed as NF-kappaB reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay
Agonist activity at STING in human THP1-Dual cells assessed as NF-kappaB reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay
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[PMID: 35108011] |
化学情報
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CAS 番号 2767442-46-4
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性状 Solid
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分子量 336.30
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分子式 C17H12N4O4
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Color Light brown to brown
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SMILES
O=C(C1=CC=CC2=C1OC(CNC(C3=C4N=CC=CN4N=C3)=O)=C2)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 62.5 mg/mL (185.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9735 mL | 14.8677 mL | 29.7354 mL | 74.3384 mL |
| 5 mM | 0.5947 mL | 2.9735 mL | 5.9471 mL | 14.8677 mL | |
| 10 mM | 0.2974 mL | 1.4868 mL | 2.9735 mL | 7.4338 mL | |
| 15 mM | 0.1982 mL | 0.9912 mL | 1.9824 mL | 4.9559 mL | |
| 20 mM | 0.1487 mL | 0.7434 mL | 1.4868 mL | 3.7169 mL | |
| 25 mM | 0.1189 mL | 0.5947 mL | 1.1894 mL | 2.9735 mL | |
| 30 mM | 0.0991 mL | 0.4956 mL | 0.9912 mL | 2.4779 mL | |
| 40 mM | 0.0743 mL | 0.3717 mL | 0.7434 mL | 1.8585 mL | |
| 50 mM | 0.0595 mL | 0.2974 mL | 0.5947 mL | 1.4868 mL | |
| 60 mM | 0.0496 mL | 0.2478 mL | 0.4956 mL | 1.2390 mL | |
| 80 mM | 0.0372 mL | 0.1858 mL | 0.3717 mL | 0.9292 mL | |
| 100 mM | 0.0297 mL | 0.1487 mL | 0.2974 mL | 0.7434 mL |
STING agonist-7 関連分類
HY-143896 関連分類
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