Sudemycin E
Sudemycin E is an analog of FR901464 (HY-16212). Sudemycin E can induce reversible changes in alternative splicing and abnormalities in chromatin modifications by binding to SF3B1, a component of the U2 small nuclear ribonucleoprotein (snRNP), thereby leading to the death of cancer cells. Sudemycin E has anti-tumor activity and can be used in tumor research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1197054-49-1
- 分子式: C27H41NO7
- 分子量:491.62
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| JeKo-1 | IC50 |
150 nM
Compound: 26
|
Cytotoxicity against human JeKo1 cells after 72 hrs by XTT assay
Cytotoxicity against human JeKo1 cells after 72 hrs by XTT assay
|
[PMID: 19877647] |
| JeKo-1 | IC50 |
220 nM
Compound: 19p
|
Cytotoxicity against human JeKo1 cells after 72 hrs by CellTiter-Glo assay
Cytotoxicity against human JeKo1 cells after 72 hrs by CellTiter-Glo assay
|
[PMID: 24325474] |
化学情報
-
CAS 番号 1197054-49-1
-
分子量 491.62
-
分子式 C27H41NO7
-
SMILES
CC(C)C(O[C@@H](C)/C=C\C(N[C@@H](CO1)CO[C@@H]1C/C=C(C)/C=C/[C@@H]2C[C@@]3(CC(C)(O2)C)CO3)=O)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Sudemycin E 関連分類
HY-120907 関連分類
Powered by Bioz