TIM-3-IN-1
Based on 1 publication(s) in Google Scholar
TIM-3-IN-1 (Compound 38) is a TIM-3 inhibitor that can be used for the research of cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.90%
- CAS 番号: 2883237-04-3
- 分子式: C20H16ClN7O3S
- 分子量:469.90
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
MedChemExpress(MCE)の使用を引用している文献 TIM-3-IN-1
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生物活性
化学情報
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CAS 番号 2883237-04-3
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性状 Solid
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分子量 469.90
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分子式 C20H16ClN7O3S
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Color Off-white to light yellow
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SMILES
CC1=NN2C(NC3=CC(Cl)=C(C4=C(C)C=C(NS(C5=NC=CN5)(=O)=O)C=C4)C=C3C2=N1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Signal
Berberine derivative C51 modulates cGAS-STING-TIM-3 axis to reverse immune evasion and inhibit lung cancer growth. [Abstract]2025 Nov 19:139:112258. PMID: 41270814
溶剤 & 溶解度
DMSO : 100 mg/mL (212.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1281 mL | 10.6406 mL | 21.2811 mL | 53.2028 mL |
| 5 mM | 0.4256 mL | 2.1281 mL | 4.2562 mL | 10.6406 mL | |
| 10 mM | 0.2128 mL | 1.0641 mL | 2.1281 mL | 5.3203 mL | |
| 15 mM | 0.1419 mL | 0.7094 mL | 1.4187 mL | 3.5469 mL | |
| 20 mM | 0.1064 mL | 0.5320 mL | 1.0641 mL | 2.6601 mL | |
| 25 mM | 0.0851 mL | 0.4256 mL | 0.8512 mL | 2.1281 mL | |
| 30 mM | 0.0709 mL | 0.3547 mL | 0.7094 mL | 1.7734 mL | |
| 40 mM | 0.0532 mL | 0.2660 mL | 0.5320 mL | 1.3301 mL | |
| 50 mM | 0.0426 mL | 0.2128 mL | 0.4256 mL | 1.0641 mL | |
| 60 mM | 0.0355 mL | 0.1773 mL | 0.3547 mL | 0.8867 mL | |
| 80 mM | 0.0266 mL | 0.1330 mL | 0.2660 mL | 0.6650 mL | |
| 100 mM | 0.0213 mL | 0.1064 mL | 0.2128 mL | 0.5320 mL |