WAY-312858
Based on 1 Customer Validation
WAY-312858 is an active molecule for the study of amyloid diseases and synucleinopathies.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.0%
- CAS 番号: 620570-09-4
- 分子式: C16H16ClFN2O3S
- 分子量:370.83
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
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Help & FAQs
生物活性
製品説明
化学情報
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CAS 番号 620570-09-4
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性状 Solid
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分子量 370.83
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分子式 C16H16ClFN2O3S
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Color White to off-white
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SMILES
CCOC(N1CCN(C(C2=C(C3=CC=C(C=C3S2)F)Cl)=O)CC1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外:
DMSO : 66.67 mg/mL (179.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
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Amyloid: Congo Red Amyloid Staining
Congo red amyloid staining is a histochemical method used to detect extracellular amyloid deposits in tissue sections based on the affinity of Congo red dye for β-pleated sheet-rich protein aggregates. When bound to amyloid, Congo red produces characteristic apple-green birefringence under polarized light microscopy, which is widely regarded as a diagnostic feature of amyloid deposition in histopathology. The diagnostic principle relies on the combination of dye binding (congophilia) and optical anisotropy under polarized illumination, which distinguishes amyloid from most non-amyloid eosinophilic extracellular deposits in routine histological evaluation. Amyloid identification by Congo red staining remains a cornerstone in diagnostic pathology despite the availability of adjunct methods such as immunohistochemistry and mass spectrometry, particularly because of its ability to localize deposits directly within tissue architecture. The specificity of Congo red-positive deposits is incre
純度とドキュメンテーション
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データシート (243 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6967 mL | 13.4833 mL | 26.9665 mL | 67.4163 mL |
| 5 mM | 0.5393 mL | 2.6967 mL | 5.3933 mL | 13.4833 mL | |
| 10 mM | 0.2697 mL | 1.3483 mL | 2.6967 mL | 6.7416 mL | |
| 15 mM | 0.1798 mL | 0.8989 mL | 1.7978 mL | 4.4944 mL | |
| 20 mM | 0.1348 mL | 0.6742 mL | 1.3483 mL | 3.3708 mL | |
| 25 mM | 0.1079 mL | 0.5393 mL | 1.0787 mL | 2.6967 mL | |
| 30 mM | 0.0899 mL | 0.4494 mL | 0.8989 mL | 2.2472 mL | |
| 40 mM | 0.0674 mL | 0.3371 mL | 0.6742 mL | 1.6854 mL | |
| 50 mM | 0.0539 mL | 0.2697 mL | 0.5393 mL | 1.3483 mL | |
| 60 mM | 0.0449 mL | 0.2247 mL | 0.4494 mL | 1.1236 mL | |
| 80 mM | 0.0337 mL | 0.1685 mL | 0.3371 mL | 0.8427 mL | |
| 100 mM | 0.0270 mL | 0.1348 mL | 0.2697 mL | 0.6742 mL |
WAY-312858 関連分類
HY-W674624 関連分類
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